We are seeking an independent and motivated Senior Associate Scientist to join our Enzyme Replacement Therapies group. As a part of Regeneron Genetics Medicine group, you will support the development of ground breaking gene therapies for treating lysosomal diseases. You will contribute to the development of new therapies using our technology platforms, including blood-brain barrier crossing, gene therapy, CRISPR-mediated gene editing, VelociGene mouse models and VelocImmune antibody platforms. We hope you are excited by the opportunity to contribute to innovative projects and further expand our targeted drug delivery portfolio in a collaborative environment.

As a Sr. Associate Scientist, a typical day might include the following:

• Planning and performing in vitro and in vivo experiments to validate the effectiveness of enzyme replacement therapies

• Performing basic molecular biology techniques (Western blotting, ELISA, enzymatic activity assays, immunofluorescence staining, plasmid cloning)

• Culturing mammalian cell lines, performing transient transfections and cell-based assays

• Conducting in vivo gene therapy studies in mice, including dosing, harvesting, and analyzing tissues

• Working collaboratively with other team members and providing support to their programs

• Participation in team meetings and preparation of regular presentations for departmental meetings

This role might be for you if you:

• Enjoy working in an innovative and highly collaborative environment

• Have an avid interest in developing gene therapies for rare diseases

• Have strong organizational, time-management, and communication skills

• Can effectively balance multiple projects

In order to be considered for this role , you must have at least a BS/MS and 3+ years of relevant experience and expertise in mouse models of human disease, cell biology, molecular biology, or related fields. Must have experience performing mouse treatment studies, mammalian cell culture, Western Blot, and ELISA. Experience with AAV gene therapies and antibody therapies strongly preferred.

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.

For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.

Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.

Salary Range (annually)

$77,600.00 - $126,600.00